Single Cell Genomics Laboratory

PML’s state-of-the-art Single Cell Genomics (SCG) Facility represents a significant advance in the molecular analysis of organisms from the environment. The bespoke facility has been designed to allow the direct isolation and characterisation of unicellular organisms and viruses from natural samples. Combining high performance and precision flow cytometry, microfluidics, liquid handling and molecular diagnostic machinery; the facility provides unprecedented genomic resolution to the field of oceanic microbial ecology. Unhindered by issues of non-culturability (a common problem with marine microbes), the SCG represents a paradigm shift in molecular biology and improves resolution of microbial or viral functional capacity and dynamics compared to metagenomic methods.

Technical specifications:

  • Clean room ISO 14644-1 ISO5 (Class 100)
  • BD Influx Flowcytometer
  • BioRad QX200 droplet digital PCR
  • Roche LightCycler480 real time PCR
  • High-Speed Atomic Force Microscope
  • Formulatrix Mantis Liquid handling
  • Hamilton MicroLab Starlet liquid handling
  • BMG LabTech CLARIOstar platereader

Key contact

Professor Mike Allen

Microbial Biochemist - mija16/01/2019

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